Post Cycle Therapy

Letrozole Half Life

Letrozole (brand name Femara including many others) is an extremely powerful Anti Estrogenic medication. It is mostly used in emergency situations when estrogen should be controlled fast and efficiently by most bodybuilders and other anabolic steroid users.


This is an orally active Aromatase Inhibitor (AI). The product is known to lower total estrogen levels in circulation. In fact, is considered the most powerful aromatase inhibitor on the market.

Letrozole (Femara) is medically used for the treatment of hormonally responsive breast cancer in post-menopausal women. But it has other medical uses too. For example ovulation induction in women, sperm boost in men, gynecomastia treatment, and various others.

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  • Nonetheless, Letrozole is a very popular product among those using anabolic steroids. That’s because it is known to quickly and sharply lower estrogen levels whenever is needed.

Letrozole Half Life and Explanation

The half life of Letrozole is considered to be 2-4 days. Therefore, the compound is going to be effective at keeping your estrogen levels lower for a while after the last dosage.

The compound, exactly as other AIs, tend to build up in the system so it requires a while until it would come in “full strength”.

Nonetheless, Letrozole is still known to work faster than other AIs as it can sharply lower down estrogens from the first administration.

Since Letrozole half life is 2-4 days, it would stay in your system for at least 4 days, up to 8 days. This depends from person to person. It has an extremely high bioavailability of 99.9%. It is being excreted from the body through the kidneys.


Keep in mind that it keeps estrogen levels low during its use, but Femara (Letrozole) is a non suicidal and non steroidal Aromatase Inhibitor (AI) which means that it doesn’t permanently disable aromatase enzymes as Exemestane does.

  • Therefore, there’s a chance of “estrogen rebound” when stopping Letrozole.

That’s why you would love to continue administering Letrozole for a while after stopping the use of steroids and slowly reducing down the dosages.

Letrozole Dosages

Femara (Letrozole) is most commonly coming in the form of oral tablets of 2.5 mg strength.

That’s because this is the most commonly prescribed dosage to women suffering from hormonally positive breast cancer (the main purpose of using Letrozole medically).

However, 2.5 mg per day of Letrozole sounds way too much for anabolic steroid users. There’s rarely anyone who needs a higher dosage than 1 mg per day.

But is not uncommon for some men to run doses as low as 0.25 mg every other day.


In the end, the dosage of Letrozole, as much as you can notice, varies a lot. That’s because it depends on a number of factors. Such as you are trying to prevent estrogen related issues, or you are trying to treat an already occurring issue (such as gynecomastia) and use it as an emergency compound.

  • It also depends on how prone you are to get estrogen related issues, how many steroids you use, their type, their dosage, for how long you’ve been running them, and so on and so forth.

Determining Letrozole dosage depends on a lot of factors. That’s why there are such huge differences in Letrozole doses.

But generally, dosages of 0.5 mg up to 1 mg per day or every other day are the most common ones.

Letrozole Side Effects

Generally, the side effects of Letrozole are very well tolerated by most men. They may not get any side effects at all as long as the compound is used properly.

Yet, some may still get them.

But because Letrozole has a half life of 2-4 days, it is believed that the side effects would quickly disappear as soon as you stop the administration of this AI. Just watch out for estrogen rebound.

  • In the end, Letrozole side effects are associated with too high dosages and therefore, too low estrogen related issues. They usually include weakness, fatigue, low sex drive, painful and dry joints, and others.


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Post Cycle Therapy

Nolvadex For Men

Tamoxifen Citrate, which is the main active substance in the brand Nolvadex or can be found as numerous other brands, is a medication that is FDA approved mainly for treating or preventing Estrogen Receptor positive (ER+) breast cancer in women. The compound also can be used for treating female infertility too. That’s why Nolvadex is mainly a medication for women.

In medical settings, Nolvadex can be used for men too, for treating gynecomastia. But still, this compound is mostly used by women, at least, in the medical world.


Nonetheless, Nolvadex for men is still very popular.

That’s because Tamoxifen has been discovered to be extremely effective at preventing or treating gynecomastia during the use of aromatized anabolic steroids so can be used on the cycle of steroids for this purpose. But it was also found out to be effective at boosting natural testosterone production.

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Nolvadex For Men PCT

That’s why Nolvadex for men is mostly used for Post Cycle Therapy (PCT) plans to boost the production of testosterone. The production is suppressed by the use of steroids during the cycle.

With this being said, Nolvadex for men who are running anabolic steroids is an extremely popular product and a very necessary one. That’s because it is very important to implement a PCT plan after each cycle with PEDs (Performance Enhancing Drugs). That’s especially true when talking about steroids.

By not implementing a PCT – you’re basically working against everything you tried to reach during the anabolic steroid cycle. That’s because the production of testosterone naturally is suppressed by steroids. When you get off them, your body does not have enough hormones (especially testosterone). With low testosterone, you lose lean muscles, lose strength, gain water and fat, feel moody, low sex drive, erectile dysfunction, etc.

That’s why TamoxifenNolvadex for men is such an important compound. It helps to maintain the gains made during the cycle and also helps you to feel well after the cycle.


As said, Nolvadex (Tamoxifen Citrate) is sometimes used during the use of anabolic steroids. That’s because the compound is going to prevent apparition or treat the already appeared gynecomastia symptoms.

  • However, it can’t really help with other estrogen related issues. That’s why Aromatase Inhibitors (AIs) are mostly used for such needs since they help with gynecomastia and other estrogenic issues too.

Nolvadex For Men Dosages

When Nolvadex is used by men for the purpose of physique and performance enhancement, the dosages highly depend on the reason why exactly you use it.

In case you run Nolvadex on cycle in order to deal with gynecomastia, then the dosage depends on whether you try to prevent or treat gynecomastia.

If used as a preventative, dosages usually are used 20 mg per day or every other day for the entire cycle. Dosages are increased or decreased depending on gynecomastia symptoms or side effects.

If used as treatment, dosages are usually started at 40-80 mg per day. It depends on gynecomastia symptoms. Then dosages might be reduced if symptoms fade away.

If you intend to use Nolvadex for PCT plan then dosages usually start at 40 mg per day. Then they are slowly brought down as the body regains the ability to produce testosterone naturally on its own.

Usually, that’s 40 mg per day for weeks 1-2. Then 20 mg per day for weeks 3-4.

PCT plans are usually 4 weeks, but they might be longer if needed.


Nolvadex For Men Side Effects

Side effects of Nolvadex (Tamoxifen Citrate) for men are almost not reported when used properly. The highest chance of getting side effects from the use of Nolvadex is when you run it improperly. Mostly – in too high doses.

  • Nolvadex side effects are unlikely to appear. Yet, some men still report increased or decreased libido, feeling emotional, dry joints, headaches, nausea, insomnia, and other issues.

There are rumors that Tamoxifen might hurt your gains, may increase progesterone, or may hurt your liver. It may be true, but it would appear only if you’re going to use the compound in way too high doses.

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Post Cycle Therapy

Buying Nolvadex Online

Anyone who is already running or at least planning on running anabolic steroids is highly recommended to consider buying Nolvadex online. That’s because Nolvadex is a compound that can be obtained only with a prescription. But no doctor would prescribe it for bodybuilding needs. So you got to buy it online from sources not asking for a prescription.

But there are numerous other advantages.

By buying Nolvadex online you make sure you get the cheapest priced compound, allowing you to save a lot of money compared to buying the compound in local pharmacies.

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In the end, as much as you can see – there are a lot of reasons why you should be buying Nolvadex online.

  • You can get it without a prescription, fast, effortlessly, of the best quality, and for the cheapest price on the market.

What is Nolvadex?

If you are still wondering why anyone who uses anabolic steroids should consider buying Nolvadex – then you should do extensive research about Post Cycle Therapy (PCT).

Nolvadex is one of the best and most popular PCT compounds out there.

The active substance in the Nolvadex brand (which can be found as numerous others) is Tamoxifen Citrate. This is an orally active medication used in medical settings for various different needs, mainly for treating breast cancer in women.

Nonetheless, Tamoxifen Citrate (Nolvadex) is used among bodybuilders all over the world.

It can be used for treating gynecomastia. This condition is likely to appear in men using aromatized steroids. But is mostly used for PCT plans.

In short – PCT is extremely important for everyone who stops running steroids. That’s in order to get back their natural hormonal system and restart the production of testosterone. Production is suppressed when using steroids.

Nolvadex PCT

We recommend buying Nolvadex online for PCT plans if you want to keep your gains after the cycle and remain healthy.

Nolvadex is often stacked with Clomid for Post Cycle Therapy – but you can find out more about this when researching PCT more.


Here is an example of Nolvadex PCT plan:

  • Week 1-2: Nolvadex used 40 mg per day (usually 2 tablets)
  • Week 3-4: Nolvadex used 20 mg per day (usually 1 tablet)

You can also add Clomid to this plan such as:

  • Week 1-2: Clomid used 50 mg per day
  • Week 3-4: Clomid used 25 mg per day

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Post Cycle Therapy

How Does Tamoxifen Work?

Tamoxifen is the main ingredient in the brand Nolvadex (sold as other brand names too) and is an orally active drug classified as an anti cancer drug in medical settings as is approved by FDA for preventing breast cancer in women and treating breast cancer in men and women. It also has other uses such as the treatment of gynecomastia and others.


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Tamoxifen, therefore, is also an anti estrogen medication, exactly as Aromatase Inhibitors (AIs) such as Aromasin – Exemestane, Arimidex – Anastrozole, and Femara – Letrozole.

Nonetheless, there’s a huge difference in how AIs and SERMs work. We are going to talk about this here.

Tamoxifen Use in Bodybuilding

In the bodybuilding world, Tamoxifen has 2 main uses – either for gynecomastia treatment or prevention or mostly as a Post Cycle Therapy drug. This compound is effective in helping users of anabolic steroids to prevent the apparition of gynecomastia (formation of breast tissue) or for treating it in case it already appeared. It also helps people who get this condition naturally.

Bodybuilders find Tamoxifen Citrate (Nolvadex) highly effective when they run aromatized steroids that are converted into estrogen in the body.

Examples of such steroids: Dianabol and Testosterone are most popular but there are many others.

In such a situation, a user is likely to get high estrogen related side effects. For example blood pressure, erectile dysfunction, water retention and one of the most common estrogen related side effects – puffy nipples. It can lead to gynecomastia.

Tamoxifen is effective to deal with gynecomastia, but is not effective in dealing with other estrogen related side effects.

That’s why bodybuilders find AIs better for such needs. And they find Tamoxifen better for PCT plans.


How Does Tamoxifen Work For Gynecomastia Prevention?

Tamoxifen CitrateNolvadex is a SERM, therefore is selectively binding to estrogen receptors blocking their actions. Tamoxifen doesn’t bind to all estrogen receptors, but selectively and mainly – in breast tissues.

Therefore, Tamoxifen is not allowing active estrogen to “do its job”. This can lead to breast cancer and gynecomastia in men. That’s why the compound is run during the cycle with steroids. It would prevent this side effect from appearing.

Nonetheless, there is the option of running AIs which are actually reducing the total flow of estrogen in the body. It not only would block the estrogen from the receptor as Nolvadex does.

Therefore, AIs would help both with gynecomastia issues and with other estrogen related side effects too.

That’s why Nolvadex (Tamoxifen) is mostly used for PCT protocols.

How Does Tamoxifen Work For PCT?

When you run anabolic steroids, the body receives signals that too many hormones are produced so it stops producing them naturally. Depending on the type, amount, dosage of steroids as well as cycle length – there are different levels of suppression.


But any anabolic steroid cycle suppresses the production of testosterone that’s why it is important to run a PCT plan to help your body recover HPTA. Tamoxifen does exactly that.

Tamoxifen Citrate is stimulating the hypothalamus for releasing more gonadotropins – the protein hormones that are secreted by the pituitary gland which are responsible for a faster and higher release of FSH and LH. As a result, you get more testosterone since Tamoxifen helps increase LH.

Therefore, you are capable of getting a boosted testosterone level, a smooth PCT and won’t get typical symptoms of getting off a steroid cycle.

  • You won’t lose muscles, gain fat, lose energy, lose sex drive, motivation etc.

As mentioned, Tamoxifen selectively binds to estrogen receptors blocking their activity – that’s how it works here too. It prevents estrogen from reaching the pituitary gland and therefore, this leads to higher production of LH. The Luteinizing Hormone (LH) offers signals to the Leydig cells for producing testosterone.

Tamoxifen is extremely effective – studies prove that users of Tamoxifen who used to have LH levels of almost 0 – they managed to reach over 10 iu (through blood works, obviously) and that’s even more than the normal reference range for an adult man.

  • Keep in mind that Tamoxifen Citrate (Nolvadex) should be used to spike your testosterone temporarily and keep you from symptoms you may get from getting off a cycle. It helps boost the recovery process but after a while, you’ve got to let your body recover on its own.

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Post Cycle Therapy

What Is Exemestane?

Exemestane is the active substance in the brand name Aromasin – the most popular brand name of Exemestane manufactured by Pfizer pharmaceutical company. Nonetheless, customers may find Exemestane being sold as various other brands except for Aromasin.

Exemestane is a new generation of drugs known as Aromatase Inhibitors. The types of drugs that are known to inhibit the process of aromatization by binding to the aromatase enzymes.

There are other notable Aromatase Inhibitors (AIs) such as Arimidex (Anastrozole) and Femara (Letrozole) that are also popular in the world of bodybuilding and athletes.

  • But Aromasin (Exemestane) is considered significantly different from the other 2 AIs. More than that, Aromasin – Exemestane is considered an even better aromatase inhibitor.


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The main reason for this is because Exemestane is a steroidal (suicidal) aromatase inhibitor. Therefore, the effects of other compounds in this class of drugs. AIs that are non-steroidal have temporary effects whilst Exemestane’s effects are permanent.

This drug is capable of suppressing estrogen levels up to about 85%. It is not going to allow estrogen to rebound as is possible with other AIs.

With this being said, many athletes and bodybuilders may receive estrogen-related symptoms when they stop administering those aromatase inhibitors. But it won’t occur with Aromasin (Exemestane).

Exemestane Uses

The compound does an amazing job in reducing the production of estrogen in the body. That’s why it is so popular among bodybuilders who use steroids. We know that a lot of steroids are converted into estrogen in the body.

Is used to control estrogen related issues.

But initially, Exemestane (Aromasin) was manufactured specifically for the treatment of breast cancer in postmenopausal women. That’s what is being approved for by FDA and what is used in medical settings.

  • That’s why you may hear of bodybuilders running cancer drugs. This is because these drugs are doing a good job of suppressing estrogens.


Exemestane Effects

To explain the effects of Exemestane, we would try to explain it easier and so, just think of this medicine like it does nothing else than binding to aromatase enzymes and this stops the aromatization process. Because of no aromatization, the total levels of estrogen hormone in the body drops.


So your body starts working and having symptoms according to higher/ lower estrogen levels.

If you use a high dosage of Exemestane (Aromasin) you are likely to get low estrogen-related issues as a result of too much eliminated estrogen.

On the other hand, if you don’t use Exemestane or not use enough of it during the use of aromatized steroids (not all steroids convert into estrogen, but bulking compounds as Dianabol and Testosterone do convert into estrogen) – you are likely to get high estrogen levels and high estrogen-related issues.

  • The estrogen is categorized in Estrone and Estradiol. A professional bodybuilder tries to keep the levels within 20-40 pg/ml of estrogen and 20-30 pg/ml estradiol for perfect results. That’s why a blood test is often recommended.

Exemestane Dosage

Is important to understand that when you run AromasinExemestane for the purpose of estrogen control during the cycle then this compound is used for the purpose of CONTROLLING the estrogen, definitely not to kill it at all.

That’s why, dosages of Exemestane highly depend on the number of steroids, types of steroids, steroids dosages, cycle length, etc. that you run.

But generally, male bodybuilders run anywhere between 12.5 mg – 25 mg of Aromasin a day. But it is not uncommon for 12.5 mg per day to be too much for them, that’s why they might use half a tablet (12.5 mg) every other day or even less frequently.

Make sure to run Exemestane in proper doses.

  • If you start receiving high estrogen related side effects such as sensitive nipples and breasts, water retention, bloating, etc. then is a good idea to increase Exemestane dosage.
  • But if you receive low estrogen related side effects like for example dry/ painful joints, low sex drive, and libido, and others, then the dosage of Exemestane should be decreased.


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