Exemestane is the active substance in the brand name Aromasin – the most popular brand name of Exemestane manufactured by Pfizer pharmaceutical company. Nonetheless, customers may find Exemestane being sold as various other brands except for Aromasin.
Exemestane is a new generation of drugs known as Aromatase Inhibitors. The types of drugs that are known to inhibit the process of aromatization by binding to the aromatase enzymes.
- But Aromasin (Exemestane) is considered significantly different from the other 2 AIs. More than that, Aromasin – Exemestane is considered an even better aromatase inhibitor.
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The main reason for this is because Exemestane is a steroidal (suicidal) aromatase inhibitor. Therefore, the effects of other compounds in this class of drugs. AIs that are non-steroidal have temporary effects whilst Exemestane’s effects are permanent.
This drug is capable of suppressing estrogen levels up to about 85%. It is not going to allow estrogen to rebound as is possible with other AIs.
With this being said, many athletes and bodybuilders may receive estrogen-related symptoms when they stop administering those aromatase inhibitors. But it won’t occur with Aromasin (Exemestane).
The compound does an amazing job in reducing the production of estrogen in the body. That’s why it is so popular among bodybuilders who use steroids. We know that a lot of steroids are converted into estrogen in the body.
Is used to control estrogen related issues.
But initially, Exemestane (Aromasin) was manufactured specifically for the treatment of breast cancer in postmenopausal women. That’s what is being approved for by FDA and what is used in medical settings.
- That’s why you may hear of bodybuilders running cancer drugs. This is because these drugs are doing a good job of suppressing estrogens.
To explain the effects of Exemestane, we would try to explain it easier and so, just think of this medicine like it does nothing else than binding to aromatase enzymes and this stops the aromatization process. Because of no aromatization, the total levels of estrogen hormone in the body drops.
So your body starts working and having symptoms according to higher/ lower estrogen levels.
If you use a high dosage of Exemestane (Aromasin) you are likely to get low estrogen-related issues as a result of too much eliminated estrogen.
On the other hand, if you don’t use Exemestane or not use enough of it during the use of aromatized steroids (not all steroids convert into estrogen, but bulking compounds as Dianabol and Testosterone do convert into estrogen) – you are likely to get high estrogen levels and high estrogen-related issues.
- The estrogen is categorized in Estrone and Estradiol. A professional bodybuilder tries to keep the levels within 20-40 pg/ml of estrogen and 20-30 pg/ml estradiol for perfect results. That’s why a blood test is often recommended.
Is important to understand that when you run Aromasin – Exemestane for the purpose of estrogen control during the cycle then this compound is used for the purpose of CONTROLLING the estrogen, definitely not to kill it at all.
That’s why, dosages of Exemestane highly depend on the number of steroids, types of steroids, steroids dosages, cycle length, etc. that you run.
But generally, male bodybuilders run anywhere between 12.5 mg – 25 mg of Aromasin a day. But it is not uncommon for 12.5 mg per day to be too much for them, that’s why they might use half a tablet (12.5 mg) every other day or even less frequently.
Make sure to run Exemestane in proper doses.
- If you start receiving high estrogen related side effects such as sensitive nipples and breasts, water retention, bloating, etc. then is a good idea to increase Exemestane dosage.
- But if you receive low estrogen related side effects like for example dry/ painful joints, low sex drive, and libido, and others, then the dosage of Exemestane should be decreased.
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